In 1890, the rough western town of Whiskey Bend, Colorado, is no place for single women. The final straw for widow Pearl Parsons and young schoolteacher Hallie Wolcott is the assault on their friend Mary. Desperately fleeing from the attacker, the three women drive away in an open wagon, seeking new lives and safety. When they're caught in a violent storm on the road, help comes in the form of a stranger, Eli Morgan.

Forced to take responsibility for the family farm when her father dies, Henry Ann Henry sees hope in the form of neighbor Tom Dolan, but a false charge of murder seems to doom their chance for happiness.

Taking a nursing job in a small town after the end of World War II, Christina Tucker finds herself being romantically pursued by her employer's two sons and is targeted in a revenge plot by one of Dr. Barlow's former disgruntled patients.