When popular, sporty sister, Kristina, is diagnosed with cancer, her younger, brainy sister, Tess, is thrown into new roles as she becomes the center of the popular crowd and must be the strong one in her family.

Twelve-year-old Fern feels invisible in her family, where grumpy eighteen-year-old Sarah is working at the family restaurant, fourteen-year-old Holden is struggling with school bullies and his emerging homosexuality, and adorable, three-year-old Charlie is always the center of attention, and when tragedy strikes, the fragile bond holding the family together is stretched almost to the breaking point.

Sixteen-year-old Bernardo, who is eight feet tall and has a condition called Gigantism, leaves the Philipines to live with his mother's family in London, much to the delight of his thirteen-year-old half sister Andi, a passionate basketball player.

After the disappearance of his sister, Cassie, and other children who ask questions about their carefully choreographed life in a domed suburb cut off from the outside world, Martin and his intelligent dog investigate.

Following the death of her father, a thirteen-year-old uses bulimia as a way to avoid her mother's and ten-year-old sister's grief, as well as her own.

Fourteen-year-old twins Adam and Rachel, pursued by both their former "Hope Project" benefactors and followers of a zombie-like figure, flee London for Paris, Seville, and finally Morocco, where they unearth an ancient secret more startling than the first.

Determined to prove herself to her legendary warrior sisters, Diana throws away her chance at glory and breaks Amazon law, risking exile, to save a mere mortal who is unwittingly fated to bring about an age of bloodshed and misery.

When fourteen-year-old twins Adam and Rachel go to visit their grandmother in an unwelcoming and ancient English village, they realize that there is something unnatural about it and are swept up in an archaeological mystery.

Resentful of having to go and live with their estranged father after the death of their mother, fifteen-year-old twins, Rich and Jade, soon find they have more complicated problems when their father is kidnapped and their attempts to rescue him involve them in a dangerous international plot to control the world's oil.

Mathilda (Tilly), fourteen, and Ruth Anne (Roo), sixteen, are sisters and best friends in Connecticut, but when Roo crashes her car while texting she is confined to a hospital bed with "locked-in syndrome," aware of her surroundings, but apparently comatose--and Tilly must find a way to communicate with her sister, while dealing with her own sense of guilt.