Presents a collection of stories of Sherlock Holmes, Dr. Watson, and friends, in a variety of eras and forms.

While on a school trip to the British Arts & Antiquities Museum, John Watson and his friends from the Baker Street Academy get involved in a mystery when the Alpine Star, a famous diamond, is stolen.

In the first of Sherlock Holmes' adventures, Dr. Watson ends up renting rooms in Baker Street with the eccentric Holmes and finds himself called upon to help the budding detective solve a perplexing mystery involving a dead body showing no sign of having been attacked found in a locked room. Holmes is convinced a murder has been committed.

In 1868, teenaged Sherlock Holmes discovers that his American tutor is hunting a notorious killer who was supposedly killed by the United States government, but who is apparently alive and well in Surrey, England.

In twenty-first-century London, Sherlock Holmes solves cases that stump Scotland Yard, assisted by his friend Dr. John Watson.

Sherlock Holmes and Dr. Watson travel to Dartmoor to solve the mystery surrounding the late Sir Charles Baskerville, a family curse, and a monsterous hound.

When the violent and unnatural death of Sir Charles Baskerville is attributed by the villagers to the curse of the Hound, an ancient ghost, Watson and Holmes arrive on the scene just in time to prevent another terrible tragedy.

Sherlock Holmes and Dr. Watson seek out their nemesis Dr. Moriarty, believed to be behind the rising tensions between European countries.